Hyaluronidase: the medical solution to correct hyaluronic acid injections

Hyaluronidase is the gold standard antidote for correcting, dissolving, or adjusting hyaluronic acid injections that have become unsightly or problematic. Used exclusively by a qualified physician, it allows for the safe restoration of a natural and harmonious result.
Lip injections for excess volume and asymmetry due to hyaluronic acid

When injections do not produce the expected result

Hyaluronic acid injections are now one of the most frequently performed cosmetic procedures, particularly for the lips. When done correctly, they hydrate, reshape, and restore volume naturally.

However, sometimes the result does not meet the patient's expectations: excessive volume, asymmetry, irregularities, product migration, or an artificial appearance. In some more serious cases, particularly after injections performed by unqualified individuals ("fake injectors"), complications can arise.

In all these situations, there is an effective and safe medical solution: hyaluronidase.


What is hyaluronidase?

Hyaluronidase is an enzyme used in aesthetic medicine as antidote to hyaluronic acidIts role is to break down the injected hyaluronic acid in order to:

  • ✨ Dissolving excess product
  • ✨ Correction of asymmetries or over-corrections
  • ✨ Treatment of certain post-injection complications
  • ✨ A return to a more natural and harmonious result

Contrary to popular belief, hyaluronidase is not reserved for emergency situations. It is increasingly used in a controlled aesthetic approach, particularly for patients wishing to return to a more natural look.


In what cases is hyaluronidase used?

1. Unsightly or unnatural results

After lip or facial injections, some patients notice:

  • Too large a volume
  • Swollen or frozen lips
  • Visible irregularities
  • An asymmetry between the upper and lower lip

Hyaluronidase then allows the result to be adjusted by partially or totally degrading the injected hyaluronic acid.

2. Trend towards a return to natural products

More and more patients today wish to reduce the volume of their lips or correct an old result that no longer suits their face. Hyaluronidase offers the possibility of gradually return to the initial appearance, before any possible further, more subtle injections.

3. Injections performed using fake injectors

Some patients seek medical help several months, or even several years, after receiving injections from unqualified individuals. These injections can lead to:

  • Persistent and unsightly volumes
  • Marked asymmetries
  • A swollen appearance that does not subside over time

In these cases, hyaluronidase is an essential tool for destroying poor quality or improperly injected hyaluronic acid.


How is a hyaluronidase injection performed?

Hyaluronidase injection is a precise medical procedure that must be performed exclusively by an experienced practitioner.

Treated areas

Depending on the problem to be corrected, hyaluronidase can be injected:

  • In the red lip
  • In the white part of the lip (above and below the lips)
  • On the upper lip and the lower lip

Injection technique

  • Injection point by point
  • The use of micro-bolus along the entire length of the lip
  • Very fine needles (34G), making the procedure painless or minimally painful

The goal is to break down the hyaluronic acid responsible for volume or irregularity in a homogeneous manner, while respecting the natural anatomy of the lips.


Results and follow-up

The effects of hyaluronidase are generally rapid. The volume gradually decreases and the lips regain a more natural and balanced appearance.

Depending on the case, a single session may be sufficient, but several adjustments may be necessary to obtain an optimal result.


Beware of illegal injections

⚠️ Hyaluronidase is a powerful medical productIf used incorrectly, it can lead to serious complications.

That is why :

  • It should never be injected by an unqualified person
  • Injections performed by unlicensed individuals pose serious and sometimes irreversible risks.

Entrusting your injections to an experienced doctor is essential to guarantee safe, precise, and elegant results. To learn more about our rates, please visit our dedicated page.


In Summary

Hyaluronidase is now an essential tool in aesthetic medicine for:

  • Correcting botched hyaluronic acid injections
  • Reduce excess volume
  • Treating certain complications
  • Achieve a natural and harmonious result

It is part of both a corrective approach and a modern aesthetic approach, focused on subtlety and respect for the face.

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Entrust your face and lips to a qualified practitioner for safe, natural and controlled results.

Dr. Nathaniel Stroumza Escoffier, plastic surgeon
Article written by the editorial team and validated by Dr. Nathaniel Stroumza Escoffier, plastic surgeon — RPPS 10100674943
Published on December 26, 2025 · Updated on March 24, 2026 · Discover the journey of Dr. Stroumza
Sources & references HAS · SOFCEP · SFCPRE · PubMed · Order of Physicians
This article is for informational purposes only and does not replace a medical consultation.

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